| 1 | Star Wars: The Force Awakens | 2015-12-15 | $245M | $992.64M | 4.05 |
| 2 | Avengers: Endgame | 2019-04-24 | $356M | $918.37M | 2.58 |
| 3 | Spider-Man: No Way Home | 2021-12-15 | $200M | $864.8M | 4.32 |
| 4 | Avengers: Infinity War | 2018-04-25 | $300M | $717.82M | 2.39 |
| 5 | Avatar: The Way of Water | 2022-12-14 | $350M | $705.81M | 2.02 |
| 6 | Deadpool & Wolverine | 2024-07-24 | $200M | $675.25M | 3.38 |
| 7 | Star Wars: The Last Jedi | 2017-12-13 | $200M | $665.18M | 3.33 |
| 8 | The Lion King | 2019-07-12 | $260M | $566.64M | 2.18 |
| 9 | Rogue One: A Star Wars Story | 2016-12-14 | $200M | $562.54M | 2.81 |
| 10 | Star Wars: The Rise of Skywalker | 2019-12-18 | $416M | $555.2M | 1.33 |
| 11 | Beauty and the Beast | 2017-03-16 | $160M | $520.31M | 3.25 |
| 12 | Avengers: Age of Ultron | 2015-04-22 | $365M | $483.6M | 1.32 |
| 13 | Black Panther: Wakanda Forever | 2022-11-09 | $250M | $481.83M | 1.93 |
| 14 | Captain Marvel | 2019-03-06 | $152M | $447.53M | 2.94 |
| 15 | Doctor Strange in the Multiverse of Madness | 2022-05-04 | $200M | $447.33M | 2.24 |
| 16 | Lilo & Stitch | 2025-05-17 | $100M | $438.28M | 4.38 |
| 17 | Guardians of the Galaxy Vol. 2 | 2017-04-19 | $200M | $406.81M | 2.03 |
| 18 | Jurassic World Dominion | 2022-06-01 | $165M | $394.01M | 2.39 |
| 19 | Avatar: Fire and Ash | 2025-12-17 | $350M | $381.58M | 1.09 |
| 20 | Guardians of the Galaxy Vol. 3 | 2023-05-03 | $250M | $376.5M | 1.51 |
| 21 | Deadpool | 2016-02-09 | $58M | $375.74M | 6.48 |
| 22 | Thor: Love and Thunder | 2022-07-06 | $250M | $372.26M | 1.49 |
| 23 | The Jungle Book | 2016-04-07 | $175M | $368.2M | 2.10 |
| 24 | Aladdin | 2019-05-22 | $183M | $362.56M | 1.98 |
| 25 | Suicide Squad | 2016-08-03 | $175M | $345.6M | 1.97 |
| 26 | Aquaman | 2018-12-07 | $160M | $344.06M | 2.15 |
| 27 | Deadpool 2 | 2018-05-10 | $110M | $343.06M | 3.12 |
| 28 | The Little Mermaid | 2023-05-18 | $297M | $308.47M | 1.04 |
| 29 | Mufasa: The Lion King | 2024-12-18 | $200M | $257.87M | 1.29 |
| 30 | Fantastic Beasts and Where to Find Them | 2016-11-16 | $180M | $242.79M | 1.35 |
| 31 | Sonic the Hedgehog 3 | 2024-12-19 | $122M | $242.62M | 1.99 |
| 32 | Doctor Strange | 2016-10-25 | $180M | $242.04M | 1.34 |
| 33 | Ant-Man and the Wasp: Quantumania | 2023-02-15 | $388M | $232.01M | 0.60 |
| 34 | Ant-Man and the Wasp | 2018-07-04 | $140M | $228.15M | 1.63 |
| 35 | Solo: A Star Wars Story | 2018-05-15 | $250M | $227.87M | 0.91 |
| 36 | Venom: Let There Be Carnage | 2021-09-30 | $110M | $225.09M | 2.05 |
| 37 | Venom | 2018-09-28 | $116M | $223.51M | 1.93 |
| 38 | Sonic the Hedgehog 2 | 2022-03-30 | $110M | $197.12M | 1.79 |
| 39 | Pirates of the Caribbean: Dead Men Tell No Tales | 2017-05-23 | $230M | $178.06M | 0.77 |
| 40 | Kingdom of the Planet of the Apes | 2024-05-08 | $160M | $177.73M | 1.11 |
| 41 | Mary Poppins Returns | 2018-12-13 | $130M | $171.96M | 1.32 |
| 42 | Fantastic Beasts: The Crimes of Grindelwald | 2018-11-14 | $200M | $168.66M | 0.84 |
| 43 | Transformers: Rise of the Beasts | 2023-06-06 | $195M | $165.87M | 0.85 |
| 44 | The SpongeBob Movie: Sponge Out of Water | 2015-01-28 | $74M | $162.99M | 2.20 |
| 45 | War for the Planet of the Apes | 2017-07-11 | $150M | $151.84M | 1.01 |
| 46 | Pokémon Detective Pikachu | 2019-05-03 | $150M | $149.81M | 1.00 |
| 47 | Sonic the Hedgehog | 2020-02-12 | $85M | $149.07M | 1.75 |
| 48 | Venom: The Last Dance | 2024-10-22 | $120M | $148.26M | 1.24 |
| 49 | Ready Player One | 2018-03-28 | $175M | $137.02M | 0.78 |
| 50 | Transformers: The Last Knight | 2017-06-16 | $217M | $135.67M | 0.63 |